Cargando…

Association of ABCB1 and FLT3 Polymorphisms with Toxicities and Survival in Asian Patients Receiving Sunitinib for Renal Cell Carcinoma

Sunitinib is a tyrosine kinase inhibitor used as first-line treatment for metastatic renal cell carcinoma (mRCC). Asian ethnicity has been previously associated with lower clearance and greater toxicities for sunitinib treatment, relative to Caucasian ethnicity. Research focusing on identifying corr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chu, Ying-Hsia, Li, Huihua, Tan, Hui Shan, Koh, Valerie, Lai, Johnathan, Phyo, Wai Min, Choudhury, Yukti, Kanesvaran, Ravindran, Chau, Noan Minh, Toh, Chee Keong, Ng, Quan Sing, Tan, Puay Hoon, Chowbay, Balram, Tan, Min-Han
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526634/ https://www.ncbi.nlm.nih.gov/pubmed/26244574 http://dx.doi.org/10.1371/journal.pone.0134102

Ejemplares similares

The Issue of Tissue in Molecular Stratification
por: Tan, Min‐Han, et al.
Publicado: (2017)

Phase I Study of Oral Vinorelbine in Combination with Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Using Two Different Schedules
por: Sutiman, Natalia, et al.
Publicado: (2016)

Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity
por: Choudhury, Yukti, et al.
Publicado: (2017)

Corrigendum: Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity
por: Choudhury, Yukti, et al.
Publicado: (2017)

Computerized Image Analysis of Tumor Cell Nuclear Morphology Can Improve Patient Selection for Clinical Trials in Localized Clear Cell Renal Cell Carcinoma
por: Um, In Hwa, et al.
Publicado: (2020)

Correction to: Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases
por: Tan, Wan-Ling, et al.
Publicado: (2018)

Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases
por: Tan, Wan-Ling, et al.
Publicado: (2018)

SLC22A1-ABCB1 Haplotype Profiles Predict Imatinib Pharmacokinetics in Asian Patients with Chronic Myeloid Leukemia
por: Singh, Onkar, et al.
Publicado: (2012)

Targeted therapy for renal cell carcinoma: The next lap
por: Kanesvaran, Ravindran, et al.
Publicado: (2014)

Myelosuppression by sunitinib is flt-3 genotype dependent
por: van Erp, N P, et al.
Publicado: (2010)

Regional registration of whole slide image stacks containing major histological artifacts
por: Paknezhad, Mahsa, et al.
Publicado: (2020)

Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
por: Jain, Amit, et al.
Publicado: (2015)

HPLC-MS/MS coupled with equilibrium dialysis method for quantification of free drug concentration of pazopanib in plasma
por: Toh, Yi Long, et al.
Publicado: (2020)

A five-gene reverse transcription-PCR assay for pre-operative classification of breast fibroepithelial lesions
por: Tan, Wai Jin, et al.
Publicado: (2016)

Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib
por: Kannan, Srinivasaraghavan, et al.
Publicado: (2017)

Meta-Analysis of ABCG2 and ABCB1 Polymorphisms With Sunitinib-Induced Toxicity and Efficacy in Renal Cell Carcinoma
por: Sun, Fengjun, et al.
Publicado: (2021)

Mentoring stages: A study of undergraduate mentoring in palliative medicine in Singapore
por: Krishna, Lalit, et al.
Publicado: (2019)

Oncologist‐patient‐caregiver decision‐making discussions in the context of advanced cancer in an Asian setting
por: Malhotra, Chetna, et al.
Publicado: (2019)

Association of Clinicopathologic and Molecular Tumor Features With Recurrence in Resected Early-Stage Epidermal Growth Factor Receptor–Positive Non–Small Cell Lung Cancer
por: Saw, Stephanie P. L., et al.
Publicado: (2021)

ABCB1 genetic variants in leukemias: current insights into treatment outcomes
por: Ankathil, Ravindran
Publicado: (2017)

Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial
por: Leung, Ying-Ying, et al.
Publicado: (2015)

Akt2: a role in breast cancer metastasis
por: Chau, Noan-Minh, et al.
Publicado: (2004)

A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples
por: Ng, Cedric Chuan-Young, et al.
Publicado: (2022)

FDG and FLT-PET for Early measurement of response to 37.5 mg daily sunitinib therapy in metastatic renal cell carcinoma
por: Horn, Kevin P., et al.
Publicado: (2015)

Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD(+) AML cell growth
por: Weir, Mark C., et al.
Publicado: (2017)

(68)Gallium-labelled PSMA-PET/CT as a diagnostic and clinical decision-making tool in Asian prostate cancer patients following prostatectomy
por: Tan, Janice S.H., et al.
Publicado: (2019)

Current standards and practice changing studies in genitourinary (GU) cancers—a review of studies in localized/early GU cancers
por: Tan, W.C., et al.
Publicado: (2022)

Metabolic profiling of HepG2 cells incubated with S(−) and R(+) enantiomers of anti-coagulating drug warfarin
por: Bai, Jing, et al.
Publicado: (2010)

Early Monitoring Antiangiogenesis Treatment Response of Sunitinib in U87MG Tumor Xenograft by (18)F-FLT MicroPET/CT Imaging
por: Bao, Xiao, et al.
Publicado: (2014)

Author Correction: Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection
por: Teo, Alvin Kuo Jing, et al.
Publicado: (2021)

Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection
por: Teo, Alvin Kuo Jing, et al.
Publicado: (2021)

Complementing Tissue Testing With Plasma Mutation Profiling Improves Therapeutic Decision-Making for Patients With Lung Cancer
por: Choudhury, Yukti, et al.
Publicado: (2022)

Abcb1a and Abcb1b genes function differentially in blood–testis barrier dynamics in the rat
por: Su, Linlin, et al.
Publicado: (2017)

A Single Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of Orally Administered Des-Aspartate Angiotensin I in Healthy Subjects
por: Lee, Ko-Onn, et al.
Publicado: (2016)

Investigations of the Optical Properties of GaNAs Alloys by First-Principle
por: Borovac, Damir, et al.
Publicado: (2017)

AlN/GaN Digital Alloy for Mid- and Deep-Ultraviolet Optoelectronics
por: Sun, Wei, et al.
Publicado: (2017)

First-Principle Study of the Optical Properties of Dilute-P GaN(1−x)P(x) Alloys
por: Borovac, Damir, et al.
Publicado: (2018)

III-Nitride Digital Alloy: Electronics and Optoelectronics Properties of the InN/GaN Ultra-Short Period Superlattice Nanostructures
por: Sun, Wei, et al.
Publicado: (2017)

DOCK2 Interacts with FLT3 and Modulates the Survival of FLT3-Expressing Leukemia Cells
por: Wu, Min, et al.
Publicado: (2016)

More microinvasive foci in larger tumours of breast ductal carcinoma in situ
por: Chen, Xiao-Yang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uvg9d3sv0gcn19gsvcdnfrjrfs