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αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
PURPOSE: To elucidate the mechanism of the induction of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) by photoreceptor outer segments (POS) and its effects on retinal pigment epithelium (RPE). METHODS: PGC-1α upregulation by POS was confirmed in ARPE-19 cells and in RPE ex viv...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526642/ https://www.ncbi.nlm.nih.gov/pubmed/26244551 http://dx.doi.org/10.1371/journal.pone.0134870 |