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Meta-Analysis of the TNFAIP3 Region in Psoriasis Reveals a Risk Haplotype that is Distinct from Other Autoimmune Diseases

TNFAIP3 encodes aubiquitin-modifying protein, A20, that is a critical regulator of inflammatory responses. TNFAIP3 polymorphisms are associated with susceptibility to multiple autoimmune diseases including psoriasis, systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, and celiac...

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Detalles Bibliográficos
Autores principales: Nititham, Joanne, Taylor, Kimberly E., Gupta, Rashmi, Chen, Haoyan, Ahn, Richard, Liu, Jianjun, Seielstad, Mark, Ma, Averil, Bowcock, Anne M., Criswell, Lindsey A., Stahle, Mona, Liao, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526682/
https://www.ncbi.nlm.nih.gov/pubmed/25521225
http://dx.doi.org/10.1038/gene.2014.75