Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome

To equalize X-linked gene dosage between the sexes in mammalian females, Xist RNA inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 in X-inactivation. Xist exon 7 is the second-largest exon with a well-conserved repeat E in eutherian mammals, but its role...

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Detalles Bibliográficos
Autores principales: Yamada, Norishige, Hasegawa, Yuko, Yue, Minghui, Hamada, Tomofumi, Nakagawa, Shinichi, Ogawa, Yuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526699/
https://www.ncbi.nlm.nih.gov/pubmed/26244333
http://dx.doi.org/10.1371/journal.pgen.1005430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526699/
https://www.ncbi.nlm.nih.gov/pubmed/26244333
http://dx.doi.org/10.1371/journal.pgen.1005430

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