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Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome
To equalize X-linked gene dosage between the sexes in mammalian females, Xist RNA inactivates one of the two X-chromosomes. Here, we report the crucial function of Xist exon 7 in X-inactivation. Xist exon 7 is the second-largest exon with a well-conserved repeat E in eutherian mammals, but its role...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526699/ https://www.ncbi.nlm.nih.gov/pubmed/26244333 http://dx.doi.org/10.1371/journal.pgen.1005430 |