Cargando…

Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation

Histone H2A monoubiquitylation (H2Aub) is considered to be a key effector in transcriptional repression by Polycomb-repressive complex 1 (PRC1). We analyzed Drosophila with a point mutation in the PRC1 subunit Sce that abolishes its H2A ubiquitylase activity or with point mutations in the H2A and H2...

Descripción completa

Detalles Bibliográficos
Autores principales: Pengelly, Ana Raquel, Kalb, Reinhard, Finkl, Katja, Müller, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526733/
https://www.ncbi.nlm.nih.gov/pubmed/26178786
http://dx.doi.org/10.1101/gad.265439.115