Cargando…

Ca(V)3.2 calcium channels control NMDA receptor-mediated transmission: a new mechanism for absence epilepsy

Ca(V)3.2 T-type calcium channels, encoded by CACNA1H, are expressed throughout the brain, yet their general function remains unclear. We discovered that Ca(V)3.2 channels control NMDA-sensitive glutamatergic receptor (NMDA-R)-mediated transmission and subsequent NMDA-R-dependent plasticity of AMPA-R...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Guangfu, Bochorishvili, Genrieta, Chen, Yucai, Salvati, Kathryn A., Zhang, Peng, Dubel, Steve J., Perez-Reyes, Edward, Snutch, Terrance P., Stornetta, Ruth L., Deisseroth, Karl, Erisir, Alev, Todorovic, Slobodan M., Luo, Jian-Hong, Kapur, Jaideep, Beenhakker, Mark P., Zhu, J. Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526737/
https://www.ncbi.nlm.nih.gov/pubmed/26220996
http://dx.doi.org/10.1101/gad.260869.115