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Ca(V)3.2 calcium channels control NMDA receptor-mediated transmission: a new mechanism for absence epilepsy
Ca(V)3.2 T-type calcium channels, encoded by CACNA1H, are expressed throughout the brain, yet their general function remains unclear. We discovered that Ca(V)3.2 channels control NMDA-sensitive glutamatergic receptor (NMDA-R)-mediated transmission and subsequent NMDA-R-dependent plasticity of AMPA-R...
Autores principales: | Wang, Guangfu, Bochorishvili, Genrieta, Chen, Yucai, Salvati, Kathryn A., Zhang, Peng, Dubel, Steve J., Perez-Reyes, Edward, Snutch, Terrance P., Stornetta, Ruth L., Deisseroth, Karl, Erisir, Alev, Todorovic, Slobodan M., Luo, Jian-Hong, Kapur, Jaideep, Beenhakker, Mark P., Zhu, J. Julius |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526737/ https://www.ncbi.nlm.nih.gov/pubmed/26220996 http://dx.doi.org/10.1101/gad.260869.115 |
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