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The host Integrator complex acts in transcription-independent maturation of herpesvirus microRNA 3′ ends

Herpesvirus saimiri (HVS) is an oncogenic γ-herpesvirus that produces microRNAs (miRNAs) by cotranscription of precursor miRNA (pre-miRNA) hairpins immediately downstream from viral small nuclear RNAs (snRNA). The host cell Integrator complex, which recognizes the snRNA 3′ end processing signal (3′...

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Detalles Bibliográficos
Autores principales: Xie, Mingyi, Zhang, Wei, Shu, Mei-Di, Xu, Acer, Lenis, Diana A., DiMaio, Daniel, Steitz, Joan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526738/
https://www.ncbi.nlm.nih.gov/pubmed/26220997
http://dx.doi.org/10.1101/gad.266973.115