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Targeting the Pim kinases in multiple myeloma

Multiple myeloma (MM) is a plasma cell malignancy that remains incurable. Novel treatment strategies to improve survival are urgently required. The Pims are a small family of serine/threonine kinases with increased expression across the hematological malignancies. Pim-2 shows highest expression in M...

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Detalles Bibliográficos
Autores principales: Keane, N A, Reidy, M, Natoni, A, Raab, M S, O'Dwyer, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526774/
https://www.ncbi.nlm.nih.gov/pubmed/26186558
http://dx.doi.org/10.1038/bcj.2015.46