PD-1(hi)TIM-3(+) T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation

Prognosis of leukemia relapse post allogeneic stem cell transplantation (alloSCT) is poor and effective new treatments are urgently needed. T cells are pivotal in eradicating leukemia through a graft versus leukemia (GVL) effect and leukemia relapse is considered a failure of GVL. T-cell exhaustion...

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Detalles Bibliográficos
Autores principales: Kong, Y, Zhang, J, Claxton, D F, Ehmann, W C, Rybka, W B, Zhu, L, Zeng, H, Schell, T D, Zheng, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526784/
https://www.ncbi.nlm.nih.gov/pubmed/26230954
http://dx.doi.org/10.1038/bcj.2015.58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526784/
https://www.ncbi.nlm.nih.gov/pubmed/26230954
http://dx.doi.org/10.1038/bcj.2015.58

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