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Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice

BACKGROUND: Recent evidence indicates that inhibition of histone deacetylase (HDAC) protects the heart against myocardial injury and stimulates endogenous angiomyogenesis. However, it remains unknown whether HDAC inhibition produces the protective effect in the diabetic heart. We sought to determine...

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Detalles Bibliográficos
Autores principales: Chen, Youfang, Du, Jianfeng, Zhao, Yu Tina, Zhang, Ling, Lv, Guorong, Zhuang, Shougang, Qin, Gangjian, Zhao, Ting C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527099/
https://www.ncbi.nlm.nih.gov/pubmed/26245924
http://dx.doi.org/10.1186/s12933-015-0262-8