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Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice
BACKGROUND: Recent evidence indicates that inhibition of histone deacetylase (HDAC) protects the heart against myocardial injury and stimulates endogenous angiomyogenesis. However, it remains unknown whether HDAC inhibition produces the protective effect in the diabetic heart. We sought to determine...
Autores principales: | Chen, Youfang, Du, Jianfeng, Zhao, Yu Tina, Zhang, Ling, Lv, Guorong, Zhuang, Shougang, Qin, Gangjian, Zhao, Ting C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527099/ https://www.ncbi.nlm.nih.gov/pubmed/26245924 http://dx.doi.org/10.1186/s12933-015-0262-8 |
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