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Transfection of brain capillary endothelial cells in primary culture with defined blood–brain barrier properties

BACKGROUND: Primary brain capillary endothelial cells (BCECs) are a promising tool to study the blood–brain barrier (BBB) in vitro, as they maintain many important characteristics of the BBB in vivo, especially when co-cultured with pericytes and/or astrocytes. A novel strategy for drug delivery to...

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Detalles Bibliográficos
Autores principales: Burkhart, Annette, Thomsen, Louiza Bohn, Thomsen, Maj Schneider, Lichota, Jacek, Fazakas, Csilla, Krizbai, István, Moos, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527128/
https://www.ncbi.nlm.nih.gov/pubmed/26246240
http://dx.doi.org/10.1186/s12987-015-0015-9