Cargando…

Transfection of brain capillary endothelial cells in primary culture with defined blood–brain barrier properties

BACKGROUND: Primary brain capillary endothelial cells (BCECs) are a promising tool to study the blood–brain barrier (BBB) in vitro, as they maintain many important characteristics of the BBB in vivo, especially when co-cultured with pericytes and/or astrocytes. A novel strategy for drug delivery to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burkhart, Annette, Thomsen, Louiza Bohn, Thomsen, Maj Schneider, Lichota, Jacek, Fazakas, Csilla, Krizbai, István, Moos, Torben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527128/ https://www.ncbi.nlm.nih.gov/pubmed/26246240 http://dx.doi.org/10.1186/s12987-015-0015-9

Ejemplares similares

The blood-brain barrier studied in vitro across species
por: Thomsen, Maj Schneider, et al.
Publicado: (2021)

A Triple Culture Model of the Blood-Brain Barrier Using Porcine Brain Endothelial cells, Astrocytes and Pericytes
por: Thomsen, Louiza Bohn, et al.
Publicado: (2015)

Role of the Blood-Brain Barrier in the Formation of Brain Metastases
por: Wilhelm, Imola, et al.
Publicado: (2013)

A novel strategy for delivering Niemann‐Pick type C2 proteins across the blood–brain barrier using the brain endothelial‐specific AAV‐BR1 virus
por: Rasmussen, Charlotte Laurfelt Munch, et al.
Publicado: (2022)

Evaluation of Targeted Delivery to the Brain Using Magnetic Immunoliposomes and Magnetic Force
por: Thomsen, Louiza Bohn, et al.
Publicado: (2019)

Blood–Brain Barrier Transport of Transferrin Receptor-Targeted Nanoparticles
por: Thomsen, Maj Schneider, et al.
Publicado: (2022)

SZR-104, a Novel Kynurenic Acid Analogue with High Permeability through the Blood–Brain Barrier
por: Molnár, Kinga, et al.
Publicado: (2021)

CB2 Receptor Activation Inhibits Melanoma Cell Transmigration through the Blood-Brain Barrier
por: Haskó, János, et al.
Publicado: (2014)

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles
por: Johnsen, Kasper Bendix, et al.
Publicado: (2018)

Development of a Novel Lipophilic, Magnetic Nanoparticle for in Vivo Drug Delivery
por: Linemann, Thomas, et al.
Publicado: (2013)

Divalent metal transporter 1 (DMT1) in the brain: implications for a role in iron transport at the blood-brain barrier, and neuronal and glial pathology
por: Skjørringe, Tina, et al.
Publicado: (2015)

Endothelial-Mesenchymal Transition of Brain Endothelial Cells: Possible Role during Metastatic Extravasation
por: Krizbai, István A., et al.
Publicado: (2015)

Transmigration of Melanoma Cells through the Blood-Brain Barrier: Role of Endothelial Tight Junctions and Melanoma-Released Serine Proteases
por: Fazakas, Csilla, et al.
Publicado: (2011)

Inflammasome activation in peritumoral astrocytes is a key player in breast cancer brain metastasis development
por: Mészáros, Ádám, et al.
Publicado: (2023)

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma
por: Johnsen, Kasper Bendix, et al.
Publicado: (2017)

Iron deficiency and iron treatment in the fetal developing brain – a pilot study introducing an experimental rat model
por: Moos, Torben, et al.
Publicado: (2018)

Pericyte‐secreted IGF2 promotes breast cancer brain metastasis formation
por: Molnár, Kinga, et al.
Publicado: (2020)

Response of the neurovascular unit to brain metastatic breast cancer cells
por: Haskó, János, et al.
Publicado: (2019)

“You Shall Not Pass”—tight junctions of the blood brain barrier
por: Bauer, Hans-Christian, et al.
Publicado: (2014)

Elasto-mechanical properties of living cells
por: Varga, Béla, et al.
Publicado: (2016)

Double-Stranded RNA Attenuates the Barrier Function of Human Pulmonary Artery Endothelial Cells
por: Bálint, Zoltán, et al.
Publicado: (2013)

Circulating ECVs prevent neurodegeneration and preserve neuronal function in a model of preclinical intracerebral hemorrhage
por: Burkhart, Annette, et al.
Publicado: (2023)

The Blood–Brain Barrier and Its Intercellular Junctions in Age-Related Brain Disorders
por: Costea, Laura, et al.
Publicado: (2019)

Focused shockwave induced blood-brain barrier opening and transfection
por: Kung, Yi, et al.
Publicado: (2018)

Impairment of the Developing Human Brain in Iron Deficiency: Correlations to Findings in Experimental Animals and Prospects for Early Intervention Therapy
por: Markova, Veronika, et al.
Publicado: (2019)

Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles
por: Kucharz, Krzysztof, et al.
Publicado: (2021)

Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation
por: Lassen, Louise Berkhoudt, et al.
Publicado: (2022)

Sonoselective transfection of cerebral vasculature without blood–brain barrier disruption
por: Gorick, Catherine M., et al.
Publicado: (2020)

pH-Responsive Lipid Nanoparticles Achieve Efficient mRNA Transfection in Brain Capillary Endothelial Cells
por: Sakurai, Yu, et al.
Publicado: (2022)

Rho-Kinase Inhibition Ameliorates Dasatinib-Induced Endothelial Dysfunction and Pulmonary Hypertension
por: Fazakas, Csilla, et al.
Publicado: (2018)

Gerardiins A–L and Structurally Related Phenanthrenes from the Halophyte Plant Juncus gerardii and Their Cytotoxicity against Triple-Negative Breast Cancer Cells
por: Stefkó, Dóra, et al.
Publicado: (2020)

Cerebral Pericytes and Endothelial Cells Communicate through Inflammasome-Dependent Signals
por: Kozma, Mihály, et al.
Publicado: (2021)

Brain-Specific Ultrastructure of Capillary Endothelial Glycocalyx and Its Possible Contribution for Blood Brain Barrier
por: Ando, Yoshiaki, et al.
Publicado: (2018)

Editorial: Targeting Neuro-Immuno-Vascular Interactions in the Brain and the Periphery
por: Wilhelm, Imola, et al.
Publicado: (2022)

Paracellular and transcellular migration of metastatic cells through the cerebral endothelium
por: Herman, Hildegard, et al.
Publicado: (2019)

Blood-brain barrier-restricted translocation of Toxoplasma gondii from cortical capillaries
por: Olivera, Gabriela C, et al.
Publicado: (2021)

Mechanisms and regulation of iron trafficking across the capillary endothelial cells of the blood-brain barrier
por: McCarthy, Ryan C., et al.
Publicado: (2015)

“Endothelial Antibody Factory” at the Blood Brain Barrier: Novel Approach to Therapy of Neurodegenerative Diseases
por: Thinard, Reynald, et al.
Publicado: (2022)

Single-cell mapping of focused ultrasound-transfected brain
por: Mathew, A. S., et al.
Publicado: (2021)

Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_n9ef21ss33ch5e5cdsaogle3t1