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Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes

[Image: see text] Squalene (SQ) is an intermediate in the biosynthesis of sterols in eukaryotes and a few bacteria and of hopanoids in bacteria where they promote membrane stability and the formation of lipid rafts in their hosts. The genes for hopanoid biosynthesis are typically located on clusters...

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Detalles Bibliográficos
Autores principales: Pan, Jian-Jung, Solbiati, Jose O., Ramamoorthy, Gurusankar, Hillerich, Brandan S., Seidel, Ronald D., Cronan, John E., Almo, Steven C., Poulter, C. Dale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527182/
https://www.ncbi.nlm.nih.gov/pubmed/26258173
http://dx.doi.org/10.1021/acscentsci.5b00115