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An artificial neural network for membrane-bound catechol-O-methyltransferase biosynthesis with Pichia pastoris methanol-induced cultures

BACKGROUND: Membrane proteins are important drug targets in many human diseases and gathering structural information regarding these proteins encourages the pharmaceutical industry to develop new molecules using structure-based drug design studies. Specifically, membrane-bound catechol-O-methyltrans...

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Detalles Bibliográficos
Autores principales: Pedro, Augusto Q, Martins, Luís M, Dias, João M L, Bonifácio, Maria J, Queiroz, João A, Passarinha, Luís A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527236/
https://www.ncbi.nlm.nih.gov/pubmed/26246150
http://dx.doi.org/10.1186/s12934-015-0304-7