Effects of different interchain linkers on biological activity of an anti-prostate cancer single-chain bispecific antibody

BACKGROUND: A single-chain bispecific antibody (scBsAb; an engineered antibody), has promising clinical applications. Nonetheless, the effect of different interchain linkers on its activity is poorly understood. METHODS: Gene synthesis was used to splice the anti-γ-seminoprotein single-chain antibod...

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Detalles Bibliográficos
Autores principales: Hao, Chao-hui, Han, Qian-he, Shan, Zhong-jie, Hu, Jian-ting, Zhang, Nan, Zhang, Xue-pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527239/
https://www.ncbi.nlm.nih.gov/pubmed/26246000
http://dx.doi.org/10.1186/s12976-015-0010-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527239/
https://www.ncbi.nlm.nih.gov/pubmed/26246000
http://dx.doi.org/10.1186/s12976-015-0010-5

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