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Effects of different interchain linkers on biological activity of an anti-prostate cancer single-chain bispecific antibody

BACKGROUND: A single-chain bispecific antibody (scBsAb; an engineered antibody), has promising clinical applications. Nonetheless, the effect of different interchain linkers on its activity is poorly understood. METHODS: Gene synthesis was used to splice the anti-γ-seminoprotein single-chain antibod...

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Detalles Bibliográficos
Autores principales:	Hao, Chao-hui, Han, Qian-he, Shan, Zhong-jie, Hu, Jian-ting, Zhang, Nan, Zhang, Xue-pei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527239/ https://www.ncbi.nlm.nih.gov/pubmed/26246000 http://dx.doi.org/10.1186/s12976-015-0010-5

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