Role of electrostatic interactions for ligand recognition and specificity of peptide transporters

BACKGROUND: Peptide transporters are membrane proteins that mediate the cellular uptake of di- and tripeptides, and of peptidomimetic drugs such as β-lactam antibiotics, antiviral drugs and antineoplastic agents. In spite of their high physiological and pharmaceutical importance, the molecular recog...

Descripción completa

Detalles Bibliográficos
Autores principales: Boggavarapu, Rajendra, Jeckelmann, Jean-Marc, Harder, Daniel, Ucurum, Zöhre, Fotiadis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527243/
https://www.ncbi.nlm.nih.gov/pubmed/26246134
http://dx.doi.org/10.1186/s12915-015-0167-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527243/
https://www.ncbi.nlm.nih.gov/pubmed/26246134
http://dx.doi.org/10.1186/s12915-015-0167-8

Ejemplares similares