Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia

Apolipoprotein C-II (APOC2) is an obligatory activator of lipoprotein lipase. Human patients with APOC2 deficiency display severe hypertriglyceridemia while consuming a normal diet, often manifesting xanthomas, lipemia retinalis and pancreatitis. Hypertriglyceridemia is also an important risk factor...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Gates, Keith P., Fang, Longhou, Amar, Marcelo J., Schneider, Dina A., Geng, Honglian, Huang, Wei, Kim, Jungsu, Pattison, Jennifer, Zhang, Jian, Witztum, Joseph L., Remaley, Alan T., Dong, P. Duc, Miller, Yury I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527288/
https://www.ncbi.nlm.nih.gov/pubmed/26044956
http://dx.doi.org/10.1242/dmm.019836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527288/
https://www.ncbi.nlm.nih.gov/pubmed/26044956
http://dx.doi.org/10.1242/dmm.019836

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