Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast

Point mutations in the human MYO1E gene, encoding class I myosin Myo1e, are associated with focal segmental glomerulosclerosis (FSGS), a primary kidney disorder that leads to end-stage kidney disease. In this study, we used a simple model organism, fission yeast Schizosaccharomyces pombe, to test th...

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Detalles Bibliográficos
Autores principales: Bi, Jing, Carroll, Robert T., James, Michael L., Ouderkirk, Jessica L., Krendel, Mira, Sirotkin, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527290/
https://www.ncbi.nlm.nih.gov/pubmed/26092123
http://dx.doi.org/10.1242/dmm.020214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527290/
https://www.ncbi.nlm.nih.gov/pubmed/26092123
http://dx.doi.org/10.1242/dmm.020214

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