Understanding the cross-resistance of oseltamivir to H1N1 and H5N1 influenza A neuraminidase mutations using multidimensional computational analyses

This study embarks on a comprehensive description of the conformational contributions to resistance of neuraminidase (N1) in H1N1 and H5N1 to oseltamivir, using comparative multiple molecular dynamic simulations. The available data with regard to elucidation of the mechanism of resistance as a resul...

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Detalles Bibliográficos
Autores principales: Singh, Ashona, Soliman, Mahmoud E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527369/
https://www.ncbi.nlm.nih.gov/pubmed/26257512
http://dx.doi.org/10.2147/DDDT.S81934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527369/
https://www.ncbi.nlm.nih.gov/pubmed/26257512
http://dx.doi.org/10.2147/DDDT.S81934

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