Early ART After Cryptococcal Meningitis Is Associated With Cerebrospinal Fluid Pleocytosis and Macrophage Activation in a Multisite Randomized Trial

Introduction. Earlier antiretroviral therapy (ART) initiation in cryptococcal meningitis resulted in higher mortality compared with deferred ART initiation (1–2 weeks vs 5 weeks postmeningitis diagnosis). We hypothesized this was due to ART-associated immune pathology, without clinically recognized...

Descripción completa

Detalles Bibliográficos
Autores principales: Scriven, James E., Rhein, Joshua, Hullsiek, Katherine Huppler, von Hohenberg, Maximilian, Linder, Grace, Rolfes, Melissa A., Williams, Darlisha A., Taseera, Kabanda, Meya, David B., Meintjes, Graeme, Boulware, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527410/
https://www.ncbi.nlm.nih.gov/pubmed/25651842
http://dx.doi.org/10.1093/infdis/jiv067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527410/
https://www.ncbi.nlm.nih.gov/pubmed/25651842
http://dx.doi.org/10.1093/infdis/jiv067

Ejemplares similares