Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies

Therapy-responsive biomarkers are an important and unmet need in the muscular dystrophy field where new treatments are currently in clinical trials. By using a comprehensive high-resolution mass spectrometry approach and western blot validation, we found that two fragments of the myofibrillar struct...

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Detalles Bibliográficos
Autores principales: Rouillon, Jérémy, Poupiot, Jérôme, Zocevic, Aleksandar, Amor, Fatima, Léger, Thibaut, Garcia, Camille, Camadro, Jean-Michel, Wong, Brenda, Pinilla, Robin, Cosette, Jérémie, Coenen-Stass, Anna M.L., Mcclorey, Graham, Roberts, Thomas C., Wood, Matthew J.A., Servais, Laurent, Udd, Bjarne, Voit, Thomas, Richard, Isabelle, Svinartchouk, Fedor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527491/
https://www.ncbi.nlm.nih.gov/pubmed/26060189
http://dx.doi.org/10.1093/hmg/ddv214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527491/
https://www.ncbi.nlm.nih.gov/pubmed/26060189
http://dx.doi.org/10.1093/hmg/ddv214

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