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Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies
Therapy-responsive biomarkers are an important and unmet need in the muscular dystrophy field where new treatments are currently in clinical trials. By using a comprehensive high-resolution mass spectrometry approach and western blot validation, we found that two fragments of the myofibrillar struct...
Autores principales: | Rouillon, Jérémy, Poupiot, Jérôme, Zocevic, Aleksandar, Amor, Fatima, Léger, Thibaut, Garcia, Camille, Camadro, Jean-Michel, Wong, Brenda, Pinilla, Robin, Cosette, Jérémie, Coenen-Stass, Anna M.L., Mcclorey, Graham, Roberts, Thomas C., Wood, Matthew J.A., Servais, Laurent, Udd, Bjarne, Voit, Thomas, Richard, Isabelle, Svinartchouk, Fedor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527491/ https://www.ncbi.nlm.nih.gov/pubmed/26060189 http://dx.doi.org/10.1093/hmg/ddv214 |
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