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Effect of methotrexate on cerebellar development in infant rats

Six-day-old rats were treated intraperitoneal injections with methotrexate 1 mg/kg, and the cerebellum was examined. Both the length and width of the vermis decreased in the methotrexate-treated group instead of the control from 4 day after treatment (DAT) onward. A significant reduction in the widt...

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Detalles Bibliográficos
Autores principales: SUGIYAMA, Akihiko, SUN, Jing, UEDA, Kota, FURUKAWA, Satoshi, TAKEUCHI, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527500/
https://www.ncbi.nlm.nih.gov/pubmed/25754651
http://dx.doi.org/10.1292/jvms.14-0475