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The Spleen Plays No Role in Nephrotoxic Serum Nephritis, but Constitutes a Place of Compensatory Haematopoiesis

BACKGROUND: The spleen has been implicated in the pathogenesis of immune-complex glomerulonephritis by initiating and resolving adaptive immune responses. Thus, we aimed to evaluate the role of the spleen in experimental nephrotoxic serum nephritis (NTS). METHODS: In order to accelerate the disease,...

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Detalles Bibliográficos
Autores principales: Artinger, Katharina, Kirsch, Alexander H., Aringer, Ida, Schabhüttl, Corinna, Rosenkranz, Alexander R., Eller, Philipp, Rho, Elena, Eller, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527588/
https://www.ncbi.nlm.nih.gov/pubmed/26247770
http://dx.doi.org/10.1371/journal.pone.0135087