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Coordinated Evolution of Influenza A Surface Proteins
The surface proteins hemagglutinin (HA) and neuraminidase (NA) of human influenza A virus evolve under selection pressures to escape adaptive immune responses and antiviral drug treatments. In addition to these external selection pressures, some mutations in HA are known to affect the adaptive lands...
Autores principales: | Neverov, Alexey D., Kryazhimskiy, Sergey, Plotkin, Joshua B., Bazykin, Georgii A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527594/ https://www.ncbi.nlm.nih.gov/pubmed/26247472 http://dx.doi.org/10.1371/journal.pgen.1005404 |
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