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RECK-Mediated β1-Integrin Regulation by TGF-β1 Is Critical for Wound Contraction in Mice

Fibroblasts are critical for wound contraction; a pivotal step in wound healing. They produce and modify the extracellular matrix (ECM) required for the proper tissue remodeling. Reversion-inducing cysteine-rich protein with Kazal motifs (RECK) is a key regulator of ECM homeostasis and turnover. How...

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Detalles Bibliográficos
Autores principales: Gutiérrez, Jaime, Droppelmann, Cristian A., Contreras, Osvaldo, Takahashi, Chiaki, Brandan, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527692/
https://www.ncbi.nlm.nih.gov/pubmed/26247610
http://dx.doi.org/10.1371/journal.pone.0135005