Chronic Dosing with Membrane Sealant Poloxamer 188 NF Improves Respiratory Dysfunction in Dystrophic Mdx and Mdx/Utrophin(-/-) Mice

Poloxamer 188 NF (national formulary (NF) grade of P-188) improves cardiac muscle function in the mdx mouse and golden retriever muscular dystrophy models. However in vivo effects on skeletal muscle have not been reported. We postulated that P-188 NF might protect diaphragm muscle membranes from con...

Descripción completa

Detalles Bibliográficos
Autores principales: Markham, Bruce E., Kernodle, Stace, Nemzek, Jean, Wilkinson, John E., Sigler, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527695/
https://www.ncbi.nlm.nih.gov/pubmed/26248188
http://dx.doi.org/10.1371/journal.pone.0134832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527695/
https://www.ncbi.nlm.nih.gov/pubmed/26248188
http://dx.doi.org/10.1371/journal.pone.0134832

Ejemplares similares