Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E(2)

INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease with very few effective treatments. The key effector cells in fibrosis are believed to be fibroblasts, which differentiate to a contractile myofibroblast phenotype with enhanced capacity to proliferate and produce ext...

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Detalles Bibliográficos
Autores principales: Epa, Amali P., Thatcher, Thomas H., Pollock, Stephen J., Wahl, Lindsay A., Lyda, Elizabeth, Kottmann, R. M., Phipps, Richard P., Sime, Patricia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527711/
https://www.ncbi.nlm.nih.gov/pubmed/26248335
http://dx.doi.org/10.1371/journal.pone.0135266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527711/
https://www.ncbi.nlm.nih.gov/pubmed/26248335
http://dx.doi.org/10.1371/journal.pone.0135266

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