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Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E(2)
INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease with very few effective treatments. The key effector cells in fibrosis are believed to be fibroblasts, which differentiate to a contractile myofibroblast phenotype with enhanced capacity to proliferate and produce ext...
Autores principales: | Epa, Amali P., Thatcher, Thomas H., Pollock, Stephen J., Wahl, Lindsay A., Lyda, Elizabeth, Kottmann, R. M., Phipps, Richard P., Sime, Patricia J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527711/ https://www.ncbi.nlm.nih.gov/pubmed/26248335 http://dx.doi.org/10.1371/journal.pone.0135266 |
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