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Receptor for Advanced Glycation End-Products Signaling Interferes with the Vascular Smooth Muscle Cell Contractile Phenotype and Function

Increased blood glucose concentrations promote reactions between glucose and proteins to form advanced glycation end-products (AGE). Circulating AGE in the blood plasma can activate the receptor for advanced end-products (RAGE), which is present on both endothelial and vascular smooth muscle cells (...

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Detalles Bibliográficos
Autores principales: Simard, Elie, Söllradl, Thomas, Maltais, Jean-Sébastien, Boucher, Julie, D’Orléans-Juste, Pédro, Grandbois, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527751/
https://www.ncbi.nlm.nih.gov/pubmed/26248341
http://dx.doi.org/10.1371/journal.pone.0128881