Bisulfite Conversion of DNA: Performance Comparison of Different Kits and Methylation Quantitation of Epigenetic Biomarkers that Have the Potential to Be Used in Non-Invasive Prenatal Testing

INTRODUCTION: Epigenetic alterations, including DNA methylation, play an important role in the regulation of gene expression. Several methods exist for evaluating DNA methylation, but bisulfite sequencing remains the gold standard by which base-pair resolution of CpG methylation is achieved. The cha...

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Detalles Bibliográficos
Autores principales: Leontiou, Chrysanthia A., Hadjidaniel, Michael D., Mina, Petros, Antoniou, Pavlos, Ioannides, Marios, Patsalis, Philippos C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527772/
https://www.ncbi.nlm.nih.gov/pubmed/26247357
http://dx.doi.org/10.1371/journal.pone.0135058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527772/
https://www.ncbi.nlm.nih.gov/pubmed/26247357
http://dx.doi.org/10.1371/journal.pone.0135058

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