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Evidence of Subclinical mtDNA Alterations in HIV-Infected Pregnant Women Receiving Combination Antiretroviral Therapy Compared to HIV-Negative Pregnant Women

INTRODUCTION: Combination antiretroviral therapy (cART) can effectively prevent vertical transmission of HIV but there is potential risk of adverse maternal, foetal or infant effects. Specifically, the effect of cART use during pregnancy on mitochondrial DNA (mtDNA) content in HIV-positive (HIV+) wo...

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Detalles Bibliográficos
Autores principales: Money, Deborah M., Wagner, Emily C., Maan, Evelyn J., Chaworth-Musters, Tessa, Gadawski, Izabelle, van Schalkwyk, Julie E., Forbes, John C., Burdge, David R., Albert, Arianne Y. K., Lohn, Zoe, Côté, Hélène C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527775/
https://www.ncbi.nlm.nih.gov/pubmed/26247211
http://dx.doi.org/10.1371/journal.pone.0135041