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Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study

BACKGROUND: Coronary Heart Disease (CHD) remains a leading cause of UK mortality, generating a large and unequal burden of disease. Dietary trans fatty acids (TFA) represent a powerful CHD risk factor, yet to be addressed in the UK (approximately 1% daily energy) as successfully as in other nations....

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Autores principales: Pearson-Stuttard, Jonathan, Critchley, Julia, Capewell, Simon, O’Flaherty, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527777/
https://www.ncbi.nlm.nih.gov/pubmed/26247848
http://dx.doi.org/10.1371/journal.pone.0132524
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author Pearson-Stuttard, Jonathan
Critchley, Julia
Capewell, Simon
O’Flaherty, Martin
author_facet Pearson-Stuttard, Jonathan
Critchley, Julia
Capewell, Simon
O’Flaherty, Martin
author_sort Pearson-Stuttard, Jonathan
collection PubMed
description BACKGROUND: Coronary Heart Disease (CHD) remains a leading cause of UK mortality, generating a large and unequal burden of disease. Dietary trans fatty acids (TFA) represent a powerful CHD risk factor, yet to be addressed in the UK (approximately 1% daily energy) as successfully as in other nations. Potential outcomes of such measures, including effects upon health inequalities, have not been well quantified. We modelled the potential effects of specific reductions in TFA intake on CHD mortality, CHD related admissions, and effects upon socioeconomic inequalities. METHODS & RESULTS: We extended the previously validated IMPACTsec model, to estimate the potential effects of reductions (0.5% & 1% reductions in daily energy) in TFA intake in England and Wales, stratified by age, sex and socioeconomic circumstances. We estimated reductions in expected CHD deaths in 2030 attributable to these two specific reductions. Output measures were deaths prevented or postponed, life years gained and hospital admissions. A 1% reduction in TFA intake energy intake would generate approximately 3,900 (95% confidence interval (CI) 3,300–4,500) fewer deaths, 10,000 (8,800–10,300) (7% total) fewer hospital admissions and 37,000 (30,100–44,700) life years gained. This would also reduce health inequalities, preventing five times as many deaths and gaining six times as many life years in the most deprived quintile compared with the most affluent. A more modest reduction (0.5%) would still yield substantial health gains. CONCLUSIONS: Reducing intake of industrial TFA could substantially decrease CHD mortality and hospital admissions, and gain tens of thousands of life years. Crucially, this policy could also reduce health inequalities. UK strategies should therefore aim to minimise industrial TFA intake.
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spelling pubmed-45277772015-08-12 Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study Pearson-Stuttard, Jonathan Critchley, Julia Capewell, Simon O’Flaherty, Martin PLoS One Research Article BACKGROUND: Coronary Heart Disease (CHD) remains a leading cause of UK mortality, generating a large and unequal burden of disease. Dietary trans fatty acids (TFA) represent a powerful CHD risk factor, yet to be addressed in the UK (approximately 1% daily energy) as successfully as in other nations. Potential outcomes of such measures, including effects upon health inequalities, have not been well quantified. We modelled the potential effects of specific reductions in TFA intake on CHD mortality, CHD related admissions, and effects upon socioeconomic inequalities. METHODS & RESULTS: We extended the previously validated IMPACTsec model, to estimate the potential effects of reductions (0.5% & 1% reductions in daily energy) in TFA intake in England and Wales, stratified by age, sex and socioeconomic circumstances. We estimated reductions in expected CHD deaths in 2030 attributable to these two specific reductions. Output measures were deaths prevented or postponed, life years gained and hospital admissions. A 1% reduction in TFA intake energy intake would generate approximately 3,900 (95% confidence interval (CI) 3,300–4,500) fewer deaths, 10,000 (8,800–10,300) (7% total) fewer hospital admissions and 37,000 (30,100–44,700) life years gained. This would also reduce health inequalities, preventing five times as many deaths and gaining six times as many life years in the most deprived quintile compared with the most affluent. A more modest reduction (0.5%) would still yield substantial health gains. CONCLUSIONS: Reducing intake of industrial TFA could substantially decrease CHD mortality and hospital admissions, and gain tens of thousands of life years. Crucially, this policy could also reduce health inequalities. UK strategies should therefore aim to minimise industrial TFA intake. Public Library of Science 2015-08-06 /pmc/articles/PMC4527777/ /pubmed/26247848 http://dx.doi.org/10.1371/journal.pone.0132524 Text en © 2015 Pearson-Stuttard et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Pearson-Stuttard, Jonathan
Critchley, Julia
Capewell, Simon
O’Flaherty, Martin
Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study
title Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study
title_full Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study
title_fullStr Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study
title_full_unstemmed Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study
title_short Quantifying the Socio-Economic Benefits of Reducing Industrial Dietary Trans Fats: Modelling Study
title_sort quantifying the socio-economic benefits of reducing industrial dietary trans fats: modelling study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527777/
https://www.ncbi.nlm.nih.gov/pubmed/26247848
http://dx.doi.org/10.1371/journal.pone.0132524
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