A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan

Proliferating eukaryotic cells undergo a finite number of cell divisions before irreversibly exiting mitosis. Yet pathways that normally limit the number of cell divisions remain poorly characterized. Here we describe a screen of a collection of 3762 single gene mutants in the yeast Saccharomyces ce...

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Detalles Bibliográficos
Autores principales: Ghavidel, Ata, Baxi, Kunal, Ignatchenko, Vladimir, Prusinkiewicz, Martin, Arnason, Terra G., Kislinger, Thomas, Carvalho, Carlos E., Harkness, Troy A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527830/
https://www.ncbi.nlm.nih.gov/pubmed/26247883
http://dx.doi.org/10.1371/journal.pgen.1005429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527830/
https://www.ncbi.nlm.nih.gov/pubmed/26247883
http://dx.doi.org/10.1371/journal.pgen.1005429

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