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Substrate Modulated Dynamics of the ADP/ATP Transporter Revealed by NMR Relaxation Dispersion

The ADP/ATP carrier (AAC) transports ADP and ATP across the inner mitochondrial membrane. Unlike most transporters that have 2-fold direct or inverted quasi-symmetry, AAC has the apparent 3-fold rotational symmetry. Further, its transport rate is fast for transporters that carry large solutes. Here,...

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Detalles Bibliográficos
Autores principales: Brüschweiler, Sven, Yang, Qin, Run, Changqing, Chou, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527935/
https://www.ncbi.nlm.nih.gov/pubmed/26167881
http://dx.doi.org/10.1038/nsmb.3059