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Substrate Modulated Dynamics of the ADP/ATP Transporter Revealed by NMR Relaxation Dispersion
The ADP/ATP carrier (AAC) transports ADP and ATP across the inner mitochondrial membrane. Unlike most transporters that have 2-fold direct or inverted quasi-symmetry, AAC has the apparent 3-fold rotational symmetry. Further, its transport rate is fast for transporters that carry large solutes. Here,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527935/ https://www.ncbi.nlm.nih.gov/pubmed/26167881 http://dx.doi.org/10.1038/nsmb.3059 |