Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction

Dysregulation of ribosome biogenesis causes human diseases, such as Diamond-Blackfan anemia, del (5q-) syndrome and bone marrow failure. However, the mechanisms of blood disorders in these diseases remain elusive. Through genetic mapping, molecular cloning and mechanism characterization of the zebra...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Xiao-E, Ma, Ke, Xu, Tao, Gao, Lei, Wu, Shuang, Fu, Cong, Zhang, Wenjuan, Wang, Zhizhang, Liu, Kaiyu, Dong, Mei, Jing, Changbin, Ren, Chunguang, Dong, Zhiwei, Chen, Yi, Jin, Yi, Huang, Qiuhua, Chang, Xing, Deng, Min, Li, Li, Luo, Lingfei, Zhu, Jun, Dang, Yongjun, Chang, Hung-Chun, Zon, Leonard I, Zhou, Yi, Chen, Saijuan, Pan, Weijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528055/
https://www.ncbi.nlm.nih.gov/pubmed/26138676
http://dx.doi.org/10.1038/cr.2015.81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528055/
https://www.ncbi.nlm.nih.gov/pubmed/26138676
http://dx.doi.org/10.1038/cr.2015.81

Ejemplares similares