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An HNF1α-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells
Hepatocytes are critical for the maintenance of liver homeostasis, but its involvement in hepatic fibrogenesis remains elusive. Hepatocyte nuclear factor 1α (HNF1α) is a liver-enriched transcription factor that plays a key role in hepatocyte function. Our previous study revealed a significant inhibi...
Autores principales: | Qian, Hui, Deng, Xing, Huang, Zhao-Wei, Wei, Ji, Ding, Chen-Hong, Feng, Ren-Xin, Zeng, Xin, Chen, Yue-Xiang, Ding, Jin, Qiu, Lei, Hu, Zhen-Lin, Zhang, Xin, Wang, Hong-Yang, Zhang, Jun-Ping, Xie, Wei-Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528057/ https://www.ncbi.nlm.nih.gov/pubmed/26169608 http://dx.doi.org/10.1038/cr.2015.84 |
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