Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome

Aicardi–Goutières syndrome (AGS) is a severe childhood inflammatory disorder that shows clinical and genetic overlap with systemic lupus erythematosus (SLE). AGS is thought to arise from the accumulation of incompletely metabolized endogenous nucleic acid species owing to mutations in nucleic acid-d...

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Detalles Bibliográficos
Autores principales: Lim, Yoong Wearn, Sanz, Lionel A, Xu, Xiaoqin, Hartono, Stella R, Chédin, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528086/
https://www.ncbi.nlm.nih.gov/pubmed/26182405
http://dx.doi.org/10.7554/eLife.08007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528086/
https://www.ncbi.nlm.nih.gov/pubmed/26182405
http://dx.doi.org/10.7554/eLife.08007

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