Immune Tolerance Maintained by Cooperative Interactions between T Cells and Antigen Presenting Cells Shapes a Diverse TCR Repertoire

The T cell population in an individual needs to avoid harmful activation by self peptides while maintaining the ability to respond to an unknown set of foreign peptides. This property is acquired by a combination of thymic and extra-thymic mechanisms. We extend current models for the development of...

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Detalles Bibliográficos
Autores principales: Best, Katharine, Chain, Benny, Watkins, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528093/
https://www.ncbi.nlm.nih.gov/pubmed/26300880
http://dx.doi.org/10.3389/fimmu.2015.00360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528093/
https://www.ncbi.nlm.nih.gov/pubmed/26300880
http://dx.doi.org/10.3389/fimmu.2015.00360

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