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The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus
As T cells develop, they migrate throughout the thymus where they undergo essential bi-directional signaling with stromal cells in distinct thymic microenvironments. Immature thymocyte progenitors are located in the thymic cortex. Following T cell receptor expression and positive selection, thymocyt...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528182/ https://www.ncbi.nlm.nih.gov/pubmed/26300884 http://dx.doi.org/10.3389/fimmu.2015.00398 |