Non-classical MHC I-E negatively regulates macrophage activation and Th17 cell development in NOD mice

Transgenic expression of I-E molecules prevents diabetes in NOD mice. So far, the precise role of these non-classical MHC II molecules remains elusive. Here, we showed that transgenic expression of I-E(k) alpha 16 molecule in NOD mice selectively reduced Th17 cells in the thymus and pancreatic drain...

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Detalles Bibliográficos
Autores principales: Yang, Chunhui, Guo, Nining, Liu, Jinhua, Yang, Juhao, Zhu, Kai, Xiao, Hui, Leng, Qibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528198/
https://www.ncbi.nlm.nih.gov/pubmed/26251280
http://dx.doi.org/10.1038/srep12941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528198/
https://www.ncbi.nlm.nih.gov/pubmed/26251280
http://dx.doi.org/10.1038/srep12941

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