NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells

Sprouting blood vessels are led by filopodia-studded endothelial tip cells that respond to angiogenic signals. Mosaic lineage tracing previously revealed that NRP1 is essential for tip cell function, although its mechanistic role in tip cells remains poorly defined. Here, we show that NRP1 is dispen...

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Detalles Bibliográficos
Autores principales: Fantin, Alessandro, Lampropoulou, Anastasia, Gestri, Gaia, Raimondi, Claudio, Senatore, Valentina, Zachary, Ian, Ruhrberg, Christiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528263/
https://www.ncbi.nlm.nih.gov/pubmed/26051942
http://dx.doi.org/10.1016/j.celrep.2015.05.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528263/
https://www.ncbi.nlm.nih.gov/pubmed/26051942
http://dx.doi.org/10.1016/j.celrep.2015.05.018

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