A Mutation in Caenorhabditis elegans NDUF-7 Activates the Mitochondrial Stress Response and Prolongs Lifespan via ROS and CED-4

The mevalonate pathway is responsible for the synthesis of cholesterol, coenzyme Q, and prenyl groups essential for small GTPase modification and function, and for the production of dolichols important for protein glycosylation. Statins, i.e., cholesterol-lowering drugs that inhibit the rate-limitin...

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Detalles Bibliográficos
Autores principales: Rauthan, Manish, Ranji, Parmida, Abukar, Ragda, Pilon, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2015
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528320/
https://www.ncbi.nlm.nih.gov/pubmed/26038366
http://dx.doi.org/10.1534/g3.115.018598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528320/
https://www.ncbi.nlm.nih.gov/pubmed/26038366
http://dx.doi.org/10.1534/g3.115.018598

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