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Glucagon-like peptide-1 protects against ischemic left ventricular dysfunction during hyperglycemia in patients with coronary artery disease and type 2 diabetes mellitus

BACKGROUND: Enhancement of myocardial glucose uptake may reduce fatty acid oxidation and improve tolerance to ischemia. Hyperglycemia, in association with hyperinsulinemia, stimulates this metabolic change but may have deleterious effects on left ventricular (LV) function. The incretin hormone, gluc...

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Detalles Bibliográficos
Autores principales: McCormick, Liam M, Heck, Patrick M, Ring, Liam S, Kydd, Anna C, Clarke, Sophie J, Hoole, Stephen P, Dutka, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528379/
https://www.ncbi.nlm.nih.gov/pubmed/26253538
http://dx.doi.org/10.1186/s12933-015-0259-3