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The analysis of clonal expansions in normal and autoimmune B cell repertoires
Clones are the fundamental building blocks of immune repertoires. The number of different clones relates to the diversity of the repertoire, whereas their size and sequence diversity are linked to selective pressures. Selective pressures act both between clones and within different sequence variants...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528416/ https://www.ncbi.nlm.nih.gov/pubmed/26194753 http://dx.doi.org/10.1098/rstb.2014.0239 |