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The analysis of clonal expansions in normal and autoimmune B cell repertoires

Clones are the fundamental building blocks of immune repertoires. The number of different clones relates to the diversity of the repertoire, whereas their size and sequence diversity are linked to selective pressures. Selective pressures act both between clones and within different sequence variants...

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Detalles Bibliográficos
Autores principales: Hershberg, Uri, Luning Prak, Eline T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528416/
https://www.ncbi.nlm.nih.gov/pubmed/26194753
http://dx.doi.org/10.1098/rstb.2014.0239