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Assigning and visualizing germline genes in antibody repertoires

Identifying the germline genes involved in immunoglobulin rearrangements is an essential first step in the analysis of antibody repertoires. Based on our prior work in analysing diverse recombinant viruses, we present IgSCUEAL (Immunoglobulin Subtype Classification Using Evolutionary ALgorithms), a...

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Detalles Bibliográficos
Autores principales: Frost, Simon D. W., Murrell, Ben, Hossain, A. S. Md. Mukarram, Silverman, Gregg J., Pond, Sergei L. Kosakovsky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528417/
https://www.ncbi.nlm.nih.gov/pubmed/26194754
http://dx.doi.org/10.1098/rstb.2014.0240